In order to provide technical support for flood control and drought relief decision-making in the Hongze Lake and the the lower reaches of Huaihe River,a simulation model is needed.The API model and Xin′anjiang model by a unit-block method dividing units for sub-catchments and unit-block for lake-inflow were used in this study.The rainfall runoff and flood hydrograph were produce based on the current situation of hydro-projects and flood retarding areas in the river basin.The mode parameters were calibrated with observation from 2000 to 2018 at sub-catchments of Bengbu,the north and south areas of the Huaihe River basin above Hongze Lake. Lake-inflow which was calculated by water balance method was regarded as the measured inflow into the Hongze Lake.The Muskingum method was used in flood confluence process of sub-catchments,and flood forecasting model into Lake was built.The results showed that the two models performed well for sub-catchments in terms of rainfall runoff simulation,especially for flood events.At rising limb,the prediction results of both models were of high accuracy.At falling limb and a long forecast periods,the prediction accuracy of the Xin′anjiang model was higher than that of the API model,and the simulated flood process was closer to the reversed deduction of lake-inflow.